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Engineering & Consulting
AGV
Clinical Manufacturing

Automation in Clinical Trial Manufacturing

Big Pharma

November 2023

Engineering & Consulting

The Challenge

Manufacturing of drugs for clinical trials is characterized by manual processes and high personnel requirements. In this specific case, extremely limited space in the existing production facility posed a massive hurdle. The goal was to develop a packaging line for bottles including transport with a mobile robot.

Identified Pain Points & Risks:

  • Downtime Risk: High dependence on manual personnel; in case of staff absences (e.g., due to epidemic situations), immediate production interruptions threaten
  • Space Constraints: The existing infrastructure offered hardly any room for standard automation solutions
  • Complexity: Large variance in bottle types (round and square up to 250ml) as well as different packing patterns in packaging boxes
  • Compliance: Necessity of a GMP-compliant system (cleanroom class C) due to integrated quality controls

Our Solution

Pharmabotix developed a customized, compact automation concept covering two core areas: packaging of vials/bottles and autonomous material transport.

System Architecture & Components:

  • LowVolume Packmate: A specially designed, compact robotic cell (footprint approx. 800 × 1700 mm) for packaging bottles including interleaf handling
  • Control & HMI: Use of state-of-the-art control technology enabling simple operation via HMI without requiring programming knowledge or the robot teach pendant
  • Flexible Gripper System: A modular concept that can handle round and square bottles and can also serve as infeed/outfeed solution for labelers in the future
  • Mobile Robot: An intelligent system for autonomous transport of pallets from central warehouse directly to production lines

Technology Highlights:

  • Smart Safety Concept: Enables box changeover by operator without interrupting the running process
  • Intelligent Recipe Management: Solves the challenge of high variance in bottles and packing patterns directly via system control
  • Counting Function: Integrated counting function for vials to ensure correct batch size

Project Gallery

Project details

Customer

Big Pharma

Industry

Engineering & Consulting

Location

Switzerland

Project Duration

3 Monate

Project Conclusion

November 2023

Key Features

  • Autonomous logistics & material flow with AGV

  • Process decoupling for skilled personnel

  • Fast ROI under 2 years

  • Space efficiency (800 × 1700 mm)

  • Scalability from 1-shift to 2-shift operation

  • GMP compliance (cleanroom class C)

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